Report on a COVID-19 Case and Concurrent Diagnosis of Chronic Myelogenous Leukemia

Abstract

Chronic myeloid leukemia (CML) represents 15% of leukemias in adults. It is characterized by the presence of the Philadelphia chromosome (Ph), the result of a reciprocal translocation between chromosomes 9 and 22 (t(9;22)). Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, some data have been obtained suggesting that patients with cancer appear to be more susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in comparison to those without neoplastic disease. However, it is not clear whether it occurs in all types of cancer. There are reports of COVID-19 infection in people with CML indicating a prevalence of 0.9%. Although it was higher than in individuals without oncological conditions, it is lower than the percentage of people hospitalized with other oncohematological diseases. We report the case of a patient who developed COVID-19 infection, and during his hospitalization, CML was diagnosed. The following are the relevant issues of the disease and the recommendations for treatment during the COVID-19 infection.

Clin Infect Immun. 2021;6(1):18-23
doi: https://doi.org/10.14740/cii121